HORDB

ID: hor003383
Uniprot ID: A0A158TFP8
Protein name: Orcokinin
Gene name: ORCK
Organism: Cancer borealis (Jonah crab)
Family: Orcokinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Cancer (genus), Cancridae (family), Cancroidea (superfamily), Heterotremata, Eubrachyura, Brachyura (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: NA

Sequence: NFDEIDRSSFG
Length: 11
Propeptide: MTRDVICTALLLALCVMASEGAIKDTPTHPANQPDAGYPADGSAAKRFDAFTTGFGHSKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSSFGFNKRNFDEIDRSSFGFVKRMLTPRDLANLYKRNFDEIDRSGFGFVRRNAE
Signal peptide: MTRDVICTALLLALCVMASEG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor003383_AF2.pdb

hor003383_ESM.pdb

Mass:	146486	Formula:	C55H79N15O21
Absent amino acids:	ACHKLMPQTVWY	Common amino acids:	DFS
pI:	3.88	Basic residues:	1
Polar residues:	4	Hydrophobic residues:	3
Hydrophobicity:	-94.55	Boman Index:	-4079
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	35.45
Instability Index:	7475.45	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 16214114
Title: Identification of Neuropeptides From the Decapod Crustacean Sinus Glands Using Nanoscale Liquid Chromatography Tandem Mass Spectrometry